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Robert
Mak
Professor of Pediatrics, Chief, Division of Pediatric Nephrology
Pediatrics
Chronic kidney disease(CKD) is associated with ‘leaky gut’, and bacterial DNA translocation; resulting in systemic inflammation. Stool operational taxonomic units (OUTs) from Brachybacterium, Catenibacterium, Enterobacteriaceae, among others, are markedly increased in CKD. We are currently studying the role of the NLRPs inflammasome on intestinal microbial flora and cachexia in CKD mice.
Kidney Diseases
Robert Mak Profile
